Intraductal papillary mucinous tumors of the pancreas
نویسندگان
چکیده
Intraductal papillary mucinous tumors (IPMTs) are benign and malignant lesions that arise from the epithelial lining of main pancreatic duct and/or branch pancreatic ducts, with excessive mucin production (especially hyperplastic/adenomatous variety). Based on the degree of cytoarchitectural atypia on microscopic examination, IPMTs are classified as benign, borderline, carcinoma in situ and invasive tumors. Imaging examinations are very important to establish the diagnosis. Two or more tests are usually required. Transabdominal ultrasound, endoscopic ultrasound, computed tomography, magnetic resonance cholangiopancreatography and endoscopic retrograde cholangiopancreatography have been used for the diagnosis of IPMTs. The correct diagnosis, achieved until recently only with endoscopic retrograde cholangiopancreatography, can be currently obtained with non-invasive imaging modalities, particularly computed tomography and magnetic resonance imaging. Confirmation of the diagnosis requires, however, endoscopic-ultrasound fine-needle aspiration biopsy, followed by cytological or microhistological exams. The natural evolution of IPMTs is still not clear and the management is consequently still evolving.
منابع مشابه
Intraductal Papillary Mucinous Tumor Simultaneously Involving the Liver and Pancreas
We describe here a 67-year-old man who was diagnosed with a rare case of intraductal papillary mucinous tumors that occurred simultaneously in the liver and pancreas. Abdominal computed tomography showed a tubular and cystic dilatation of the pancreatic duct in the pancreas tail, which suggested an intraductal papillary mucinous tumor (IPMT), and multiple intrahepatic duct stones. The patient u...
متن کاملIntraductal papillary mucinous tumors of the pancreas: incidence, clinical findings and natural history.
Intraductal papillary-mucinous tumors of the pancreas are a category of recently described tumors of the exocrine pancreas. They were reported for the first time in 1982 [1] when Ohashi et al., based on the findings of four cases of mucous secreting pancreatic cancer, theorized that those cases belonged to a group of tumors with different features with respect to common pancreatic cancer. Some ...
متن کاملIntraductal papillary mucinous neoplasm of the pancreas: an emerging indication for surgical therapy.
differential diagnosis a need when cystic profile lesions are found in the pancreas (1,2). And of course intraductal papillary mucinous neoplasm of the pancreas must be carefully assessed in the differential diagnosis of such lesions. For every finding that is cystic in nature a first step is always to tell tumors, whether benign or malignant, from non-neoplastic conditions. To consider a cysti...
متن کاملIntraductal oncocytic papillary neoplasm of the pancreas: report of a case requiring completion pancreatectomy.
CONTEXT Cystic tumors of the pancreas have been diagnosed with increasing frequency. Intraductal oncocytic papillary neoplasm is a rare type of cystic pancreatic tumor. Intraductal oncocytic papillary neoplasm is considered a distinct entity with the potential of developing into invasive carcinoma and it should be differentiated from other cystic tumors of the pancreas, including mucinous cysti...
متن کاملSub-branch and mixed-type intraductal papillary mucinous neoplasms of the pancreas: 2 case reports.
Intraductal papillary mucinous neoplasia (IPMN) is one of the cystic neoplasias of the pancreas. The imaging findings provide that these tumors are differentiated from the other cystic lesions of the pancreas, especially from the chronic pancreatitis, where the treatment protocol is completely different. Therefore, the correct diagnosis and classification of the IPMN ensures that the patient re...
متن کامل